RESUMO
The aim of this study was to assess dual-task performance in TBI patients, under different experimental conditions, with or without explicit emphasis on one of two tasks. Results were compared with measurement of the subjective mental effort required to perform each task. Forty-three severe TBI patients at the subacute or chronic phase performed two tasks under single- and dual-task conditions: (a) random generation; (b) visual go-no go reaction time task. Three dual-task conditions were given, requiring either to consider both tasks as equally important or to focus preferentially on one of them. Patients were compared to matched controls. Subjective mental effort was rated on a visual analogic scale. TBI patients showed a disproportionate increase in reaction time in the go-no go task under the dual-task condition. However, they were just as able as controls to adapt performance to the specific instructions about the task to be emphasised. Patients reported significantly higher subjective mental effort, but the variation of mental effort according to task condition was similar to that of controls. These results suggest that the divided attention deficit of TBI patients is related to a reduction in available processing resources rather than an impairment of strategic processes responsible for attentional allocation and switching. The higher level of subjective mental effort may explain why TBI patients frequently complain of mental fatigue, although this subjective complaint seems to be relatively independent of cognitive impairment.
Assuntos
Atenção/fisiologia , Lesões Encefálicas/complicações , Comportamento de Escolha/fisiologia , Transtornos Cognitivos/etiologia , Fadiga Mental/etiologia , Tempo de Reação/fisiologia , Adulto , Lesões Encefálicas/fisiopatologia , Transtornos Cognitivos/diagnóstico , Transtornos Cognitivos/fisiopatologia , Aprendizagem por Discriminação/fisiologia , Feminino , Traumatismos Cranianos Fechados/complicações , Traumatismos Cranianos Fechados/fisiopatologia , Humanos , Masculino , Análise por Pareamento , Fadiga Mental/diagnóstico , Mascaramento Perceptivo , Valores de Referência , Índice de Gravidade de DoençaRESUMO
Partant d'une conception cybernetique, axee sur le processus d'information et la notion du computo d'Edgard Morin, cette etude vise a expliquer - les grandes lois de l'homoeopathie - la physiologie cellulaire - la cancerologie de la cellule - les moyens de l'eviter. En decoule l'hypothese d'action des ADN-ARN dynamises en cancerologie. Les developpements recents de cette methode therapeutique sont ensuite abordes notamment dans le cadre des applications cliniques actuelles au niveau universitaire et dans de grands centres de cancerologie
